A2A Receptor Antagonism and Dyskinesia in Parkinson’s Disease

Dyskinesia, a major complication of treatment of Parkinson’s disease (PD), involves two phases: induction, which is responsible for dyskinesia onset, and expression, which underlies its clinical manifestation. The unique cellular and regional distribution of adenosine A2A receptors in basal ganglia...

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Bibliographic Details
Main Authors: Micaela Morelli, Fabio Blandini, Nicola Simola, Robert A. Hauser
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2012/489853