Feasibility of drug delivery to the eye's posterior segment by topical instillation of PLGA nanoparticles

Feasibility of drug delivery to the eye's posterior segment by topical instillation of PLGA nanoparticles

We investigated the delivery of drugs to the posterior segment of the eye by non-invasive topical instillation using submicron-sized poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles (NPs). Surface-modified PLGA NPs were developed to improve the drug delivery efficiency to the retina and were admi...

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Bibliographic Details
Main Authors: Kohei Tahara, Keiichi Karasawa, Risako Onodera, Hirofumi Takeuchi
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
PLGA
Nanoparticles
Topical instillation
Retina
Surface modification
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087617300387

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http://www.sciencedirect.com/science/article/pii/S1818087617300387

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