Knockdown of circRNA circ_0087378 Represses the Tumorigenesis and Progression of Esophageal Squamous Cell Carcinoma Through Modulating the miR-140-3p/E2F3 Axis

Knockdown of circRNA circ_0087378 Represses the Tumorigenesis and Progression of Esophageal Squamous Cell Carcinoma Through Modulating the miR-140-3p/E2F3 Axis

BackgroundWe aimed to investigate the function and underlying mechanisms of circ_0087378 in esophageal squamous cell carcinoma (ESCC).MethodsWe verified higher circ_0087378 expression in ESCC tissues by performing qRT-PCR assays. We further confirmed the oncogenic roles of circ_0087378 in ESCC cells...

Full description

Bibliographic Details
Main Authors: Jing Wang, Qiushuang Wang, Yi Gong, Qiu Hu, Haoliang Zhang, Shaobo Ke, Yongshun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma
circ_0087378
miR-140-3p
E2F3
cancer progression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.607231/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.607231/full

Similar Items