A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease

A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease

Abstract Introduction The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 (sTREM2), a proxy of microglial activity, is associated with clinica...

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Bibliographic Details
Main Authors: Trine Holt Edwin, Kristi Henjum, Lars N.G. Nilsson, Leiv Otto Watne, Karin Persson, Rannveig Sakshaug Eldholm, Ingvild Saltvedt, Nathalie Bodd Halaas, Geir Selbæk, Knut Engedal, Bjørn Heine Strand, Anne‐Brita Knapskog
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Alzheimer's disease
Clinical Dementia Rating scale
disease progression
soluble triggering receptor expressed on myeloid cells 2 (sTREM2)
trajectories
Online Access:https://doi.org/10.1002/dad2.12128

Internet

https://doi.org/10.1002/dad2.12128

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