Clinical Significance of Telomerase Reverse-Transcriptase Promoter Mutations in Hepatocellular Carcinoma

Clinical Significance of Telomerase Reverse-Transcriptase Promoter Mutations in Hepatocellular Carcinoma

Telomerase reactivation during hepatocarcinogenesis is recurrently caused by two point mutations occurring most frequently at the nucleotide −124 (95%) and occasionally at the nucleotide −146 (<5%) upstream of the TERT translational start site in hepatocellular carcinoma (HCC). In this study, we...

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Bibliographic Details
Main Authors: Francesca Pezzuto, Francesco Izzo, Pasquale De Luca, Elio Biffali, Luigi Buonaguro, Fabiana Tatangelo, Franco Maria Buonaguro, Maria Lina Tornesello
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
TERT promoter
TERTp
hepatocellular carcinoma
HCC
droplet digital PCR
ddPCR
Online Access:https://www.mdpi.com/2072-6694/13/15/3771

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https://www.mdpi.com/2072-6694/13/15/3771

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