Integrative comparison of the genomic and transcriptomic landscape between prostate cancer patients of predominantly African or European genetic ancestry.

Men of predominantly African Ancestry (AA) have higher prostate cancer (CaP) incidence and worse survival than men of predominantly European Ancestry (EA). While socioeconomic factors drive this disparity, genomic factors may also contribute to differences in the incidence and mortality rates. To co...

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Bibliographic Details
Main Authors: Jiao Yuan, Kevin H Kensler, Zhongyi Hu, Youyou Zhang, Tianli Zhang, Junjie Jiang, Mu Xu, Yutian Pan, Meixiao Long, Kathleen T Montone, Janos L Tanyi, Yi Fan, Rugang Zhang, Xiaowen Hu, Timothy R Rebbeck, Lin Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008641