Pentixafor PET/CT for imaging of chemokine receptor 4 expression in esophageal cancer – a first clinical approach

Abstract Background Expression of CXCR4, a chemokine (C-X-C motif) receptor that plays a central role in tumor growth and metastasis of circulating tumor cells, has been described in a variety of solid tumors. A high expression of CXCR4 has a prognostic significance with regard to overall and progre...

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Main Authors: Philipp Linde, Christian Baues, Simone Wegen, Maike Trommer, Alexander Quaas, Johannes Rosenbrock, Eren Celik, Simone Marnitz, Christiane J. Bruns, Thomas Fischer, Klaus Schomaecker, Hans-Juergen Wester, Alexander Drzezga, Lutz van Heek, Carsten Kobe
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cancer Imaging
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Online Access:https://doi.org/10.1186/s40644-021-00391-w