FAM64A is an androgen receptor-regulated feedback tumor promoter in prostate cancer

Abstract Endocrine therapy for prostate cancer (PCa) mainly inhibits androgen receptor (AR) signaling, due to increased androgen synthesis and AR changes, PCa evolved into castration-resistant prostate cancer (CRPC). The function of Family With Sequence Similarity 64 Member A (FAM64A) and its associ...

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Bibliographic Details
Main Authors: Yingchen Zhou, Longhua Ou, Jinming Xu, Haichao Yuan, Junhua Luo, Bentao Shi, Xianxin Li, Shangqi Yang, Yan Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03933-z