BAFF Inhibition Effectively Suppresses the Development of Anti-HLA.A2 Antibody in the Highly Sensitized Mouse Model

BAFF Inhibition Effectively Suppresses the Development of Anti-HLA.A2 Antibody in the Highly Sensitized Mouse Model

B cell activating factor (BAFF) is a cytokine that plays a role in the survival, proliferation and differentiation of B cells. We proposed to observe the effects of BAFF inhibition on the humoral immune responses of an allosensitized mouse model using HLA.A2 transgenic mice. Wild-type C57BL/6 mice w...

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Bibliographic Details
Main Authors: Ji Won Min, Yoo-Jin Shin, Hyeyoung Lee, Bo-Mi Kim, Ki Hyun Park, Kyoung Chan Doh, Tae-Min Kim, Sun Woo Lim, Chul Woo Yang, Eun-Jee Oh, Byung Ha Chung
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
HLA.A2 transgenic mice
sensitization
skin allograft
BAFF
donor-specific antibody
Online Access:https://www.mdpi.com/1422-0067/22/2/861

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https://www.mdpi.com/1422-0067/22/2/861

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