5,6-DiHETE attenuates vascular hyperpermeability by inhibiting Ca2+ elevation in endothelial cells

Although more than 100 lipid metabolites have been identified, their bioactivities remain unknown. In a previous study, we discovered that the production of several lipid metabolites in the intestines dramatically changed in colitis. Of these metabolites, 5,6-dihydroxyeicosatetraenoic acid (DiHETE)...

Full description

Bibliographic Details
Main Authors: Taiki Hamabata, Tatsuro Nakamura, Yuri Tachibana, Daiki Horikami, Takahisa Murata
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752034178X