Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection

Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection

Abstract Background Current immunosuppressive medications used after transplantation induce significant toxicity , and a new medication regimen is needed. Based on recent research, Sirt1 exerts a proinflammatory effect on the immune response. Sirtinol is a Sirt1 inhibitor, but its impact on allograf...

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Bibliographic Details
Main Authors: Qing Ye, Mingjian Zhang, Yang Wang, Shangxi Fu, Shu Han, Liming Wang, Quanxing Wang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cell & Bioscience
Subjects:
Sirtinol
Allograft rejection
Th17/Treg
Online Access:http://link.springer.com/article/10.1186/s13578-017-0182-2

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http://link.springer.com/article/10.1186/s13578-017-0182-2

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