Deregulation of Exo70 Facilitates Innate and Acquired Cisplatin Resistance in Epithelial Ovarian Cancer by Promoting Cisplatin Efflux

Deregulation of Exo70 Facilitates Innate and Acquired Cisplatin Resistance in Epithelial Ovarian Cancer by Promoting Cisplatin Efflux

Whilst researches elucidating a diversity of intracellular mechanisms, platinum-resistant epithelial ovarian cancer (EOC) remains a major challenge in the treatment of ovarian cancer. Here we report that Exo70, a key subunit of the exocyst complex, contributes to both innate and acquired cisplatin r...

Full description

Bibliographic Details
Main Authors: Yujie Zhao, Xiaoting Hong, Xiong Chen, Chun Hu, Weihong Lu, Baoying Xie, Linhai Zhong, Wenqing Zhang, Hanwei Cao, Binbin Chen, Qian Liu, Yanyan Zhan, Li Xiao, Tianhui Hu
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
Exo70
cisplatin resistance
epithelial ovarian cancer
autophagy
Online Access:https://www.mdpi.com/2072-6694/13/14/3467

Internet

https://www.mdpi.com/2072-6694/13/14/3467

Similar Items