PDCD6 cooperates with C-Raf to facilitate colorectal cancer progression via Raf/MEK/ERK activation

PDCD6 cooperates with C-Raf to facilitate colorectal cancer progression via Raf/MEK/ERK activation

Abstract Background Colorectal cancer (CRC) is one of the most common malignancies, and it’s expected that the CRC burden will substantially increase in the next two decades. New biomarkers for targeted treatment and associated molecular mechanism of tumorigenesis remain to be explored. In this stud...

Full description

Bibliographic Details
Main Authors: Xiaojuan Wang, Fan Wu, Han Wang, Xiaoyuan Duan, Rong Huang, Amannisa Tuersuntuoheti, Luying Su, Shida Yan, Yuechao Zhao, Yan Lu, Kai Li, Jinjie Yao, Zhiwen Luo, Lei Guo, Jianmei Liu, Xiao Chen, Yalan Lu, Hanjie Hu, Xingchen Li, Mandula Bao, Xinyu Bi, Boyu Du, Shiying Miao, Jianqiang Cai, Linfang Wang, Haitao Zhou, Jianming Ying, Wei Song, Hong Zhao
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
PDCD6
Colorectal cancer
Growth
MAPK signaling pathway
Online Access:http://link.springer.com/article/10.1186/s13046-020-01632-9

Internet

http://link.springer.com/article/10.1186/s13046-020-01632-9

Similar Items