CFTR Deficiency Affects Glucose Homeostasis via Regulating GLUT4 Plasma Membrane Transportation

CFTR Deficiency Affects Glucose Homeostasis via Regulating GLUT4 Plasma Membrane Transportation

Cystic Fibrosis (CF) is an autosomal recessive disorder caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene. CF-related diabetes (CFRD) is one of the most prevalent comorbidities of CF. Altered glucose homeostasis has been reported in CF patients. The mechanism...

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Bibliographic Details
Main Authors: Junzhong Gu, Weiwei Zhang, Lida Wu, Yuchun Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cystic fibrosis
CFTR
CF-related diabetes
glucose homeostasis disorder
GLUT4
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.630654/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.630654/full

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