Modulation of the Immune Response to DNA Vaccine Encoding Gene of 8-kDa Subunit of Echinococcus granulosus Antigen B Using Murine Interleukin-12 Plasmid in BALB/c Mice

Modulation of the Immune Response to DNA Vaccine Encoding Gene of 8-kDa Subunit of Echinococcus granulosus Antigen B Using Murine Interleukin-12 Plasmid in BALB/c Mice

Background: The current study was designed to evaluate immune responses induced by DNA vaccines encoding 8-kDa subunit of antigen B (HydI) of Echinococcus granulosus and murine interleukin 12 (IL-12) as genetic adjuvants in BALB/c mice. Methods: Expression plasmid pcDNA3.1 containing HydI (pcHyd1)...

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Bibliographic Details
Main Authors: Hakim AZIZI, Bahram KAZEMI, Mojgan BANDEHPOUR, Mehdi MOHEBALI, Ali KHAMESIPOUR, Mojgan ARYAEIPOUR, Hajar YAGHOOBI, Mohammad Bagher ROKNI
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-12-01
Series:Iranian Journal of Parasitology
Subjects:
Hydatid disease
Th1/Th2
Cytokines
Immunization
Genetic adjuvant
Antigen B
Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1347

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https://ijpa.tums.ac.ir/index.php/ijpa/article/view/1347

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