The Vasorelaxant Mechanisms of a Rho Kinase Inhibitor DL0805 in Rat Thoracic Aorta

The Vasorelaxant Mechanisms of a Rho Kinase Inhibitor DL0805 in Rat Thoracic Aorta

Rho-kinase has been suggested as a potential therapeutic target in the treatment of cardiovascular diseases. The Rho-kinase signaling pathway is substantially involved in vascular contraction. The aim of the present study was to evaluate the vasorelaxant effects of Rho kinase inhibitor DL0805 in iso...

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Bibliographic Details
Main Authors: Guanhua Du, Liping Wang, Kun Si, Xiaozhen Jiao, Ping Xie, Lili Gong, Lianhua Fang, Jianhao Peng
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Molecules
Subjects:
DL0805
vasorelaxation
Rho kinase
aorta
endothelium
nitric oxide
Online Access:http://www.mdpi.com/1420-3049/17/5/5935

Internet

http://www.mdpi.com/1420-3049/17/5/5935

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