Suppression of Th17 cell differentiation via sphingosine-1-phosphate receptor 2 by cinnamaldehyde can ameliorate ulcerative colitis

Ulcerative colitis (UC) is chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum. Although the etiology is unknown, dysregulation of the intestinal mucosal immune system is closely related to UC. Cinnamaldehyde (CA) is a major active compound from cinnamon, is k...

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Bibliographic Details
Main Authors: Shu-lan Qu, Long Chen, Xue-shan Wen, Jian-ping Zuo, Xiao-yu Wang, Zhi-jie Lu, Yi-fu Yang
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220313093