Preparation of trinucleotide phosphoramidites as synthons for the synthesis of gene libraries

The preparation of protein libraries is a key issue in protein engineering and biotechnology. Such libraries can be prepared by a variety of methods, starting from the respective gene library. The challenge in gene library preparation is to achieve controlled total or partial randomization at any pr...

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Bibliographic Details
Main Authors: Ruth Suchsland, Bettina Appel, Sabine Müller
Format: Article
Language:English
Published: Beilstein-Institut 2018-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.14.28