Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity

Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity

Reduced activity of nutrient-sensing signaling networks can extend organismal lifespan, yet the underlying biology remains unclear. We show that the anti-aging effects of rapamycin and reduced intestinal insulin/insulin growth factor (IGF) signaling (IIS) require the Drosophila FoxA transcription fa...

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Bibliographic Details
Main Authors: Ekin Bolukbasi, Mobina Khericha, Jennifer C. Regan, Dobril K. Ivanov, Jennifer Adcott, Miranda C. Dyson, Tobias Nespital, Janet M. Thornton, Nazif Alic, Linda Partridge
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Subjects:
longevity
insulin
enterocytes
lifespan
midgut
Drosophila
absorption
FOXA
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717313177

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http://www.sciencedirect.com/science/article/pii/S2211124717313177

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