Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine

Immune response characterization in a human challenge study with a Shigella flexneri 2a bioconjugate vaccine

Background: Diarrheal diseases are a leading cause of global morbidity and mortality affecting all ages, but especially children under the age of five in resource-limited settings. Shigella is a leading contributor to diarrheal diseases caused by bacterial pathogens and is considered a significant a...

Full description

Bibliographic Details
Main Authors: Kristen A. Clarkson, Kawsar R. Talaat, Cristina Alaimo, Patricia Martin, A. Louis Bourgeois, Anita Dreyer, Chad K. Porter, Subhra Chakraborty, Jessica Brubaker, Daniel Elwood, Rahel Frölich, Barbara DeNearing, Hailey P. Weerts, Brittany Feijoo, Jane Halpern, David Sack, Mark S. Riddle, Veronica Gambillara Fonck, Robert W. Kaminski
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:EBioMedicine
Subjects:
Shigella
Immunogenicity
Bioconjugate vaccine
Human challenge
Gut-homing responses
Parenteral immunization
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421001018

Internet

http://www.sciencedirect.com/science/article/pii/S2352396421001018

Similar Items