Novel meso-substituted porphyrin derivatives and its potential use in photodynamic therapy of cancer

Novel meso-substituted porphyrin derivatives and its potential use in photodynamic therapy of cancer

Abstract Background Photodynamic therapy (PDT) is an anticancer treatment that utilizes the interaction of light and a photosensitiser (PS), promoting tumour cell death mediated by generation of reactive oxygen species. In this study, we evaluated the in vitro photoactivity of four meso-substituted...

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Bibliographic Details
Main Authors: Pablo Vallecorsa, Gabriela Di Venosa, M. Belén Ballatore, Dario Ferreyra, Leandro Mamone, Daniel Sáenz, Gustavo Calvo, Edgardo Durantini, Adriana Casas
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Cancer
Subjects:
Photodynamic therapy
Porphyrins
Cancer
Photosensitisers
Cells
Mice
Online Access:https://doi.org/10.1186/s12885-021-08286-6

Internet

https://doi.org/10.1186/s12885-021-08286-6

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