Neoantigens and genome instability: impact on immunogenomic phenotypes and immunotherapy response

Abstract The resurgence of immune therapies in cancer medicine has elicited a corresponding interest in understanding the basis of patient response or resistance to these treatments. One aspect of patient response clearly lies in the genomic alterations that are associated with cancer onset and prog...

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Bibliographic Details
Main Author: Elaine R. Mardis
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-019-0684-0