Targeting connexins with Gap27 during cold storage of the human donor uterus protects against cell death.

Uterus transplantation is an experimental infertility treatment for women with uterine factor infertility. During donor uterus retrieval and subsequent storage, ischemia and other stressors are likely to occur, resulting in the delayed restoration of organ function and increased graft rejection. The...

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Bibliographic Details
Main Authors: Katarzyna J Szymanska, Menekse Göker, Melissa Bol, Jo Van Dorpe, Steven Weyers, Luc Leybaert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243663