Minor Type IV Collagen α5 Chain Promotes Cancer Progression through Discoidin Domain Receptor-1.

Type IV collagens (Col IV), components of basement membrane, are essential in the maintenance of tissue integrity and proper function. Alteration of Col IV is related to developmental defects and diseases, including cancer. Col IV α chains form α1α1α2, α3α4α5 and α5α5α6 protomers that further form c...

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Bibliographic Details
Main Authors: Qian Xiao, Yan Jiang, Qingbo Liu, Jiao Yue, Chunying Liu, Xiaotong Zhao, Yuemei Qiao, Hongbin Ji, Jianfeng Chen, Gaoxiang Ge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4438069?pdf=render