Protein dynamics and conformational selection in bidirectional signal transduction
<p>Abstract</p> <p>Protein conformational dynamics simultaneously allow promiscuity and specificity in binding. The multiple conformations of the free EphA4 ligand-binding domain observed in two new EphA4 crystal structures provide a unique insight into the conformational dynamics...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-01-01
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| Series: | BMC Biology |
| Online Access: | http://www.biomedcentral.com/1741-7007/10/2 |