Combining Mathematical Models With Experimentation to Drive Novel Mechanistic Insights Into Macrophage Function

This perspective outlines an approach to improve mechanistic understanding of macrophages in inflammation and tissue homeostasis, with a focus on human inflammatory bowel disease (IBD). The approach integrates wet-lab and in-silico experimentation, driven by mechanistic mathematical models of releva...

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Bibliographic Details
Main Authors: Joanneke E. Jansen, Eamonn A. Gaffney, Jonathan Wagg, Mark C. Coles
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
IBD
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01283/full