Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylation.

Malignant pleural mesothelioma (MPM) is a devastating disease with an overall poor prognosis. Despite the recent advances in targeted molecular therapies, there is a clear and urgent need for the identification of novel mesothelioma targets for the development of highly efficacious therapeutics.In t...

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Bibliographic Details
Main Authors: Satish Kalari, Nagabhushan Moolky, Srikanth Pendyala, Evgeny V Berdyshev, Cleo Rolle, Rajani Kanteti, Archana Kanteti, Wenli Ma, Donghong He, Aliya N Husain, Hedy L Kindler, Prasad Kanteti, Ravi Salgia, Viswanathan Natarajan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3444486?pdf=render