Type 2 diabetes elicits lower nitric oxide, bradykinin concentration and kallikrein activity together with higher DesArg(9)-BK and reduced post-exercise hypotension compared to non-diabetic condition.

This study compared the plasma kallikrein activity (PKA), bradykinin concentration (BK), DesArg(9)-BK production, nitric oxide release (NO) and blood pressure (BP) response after moderate-intensity aerobic exercise performed by individuals with and without type 2 diabetes. Ten subjects with type 2 d...

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Main Authors: Herbert Gustavo Simões, Ricardo Yukio Asano, Marcelo Magalhães Sales, Rodrigo Alberto Vieira Browne, Gisela Arsa, Daisy Motta-Santos, Guilherme Morais Puga, Laila Cândida de Jesus Lima, Carmen Sílvia Grubert Campbell, Octavio Luiz Franco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24265812/?tool=EBI