Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during Xenopus tropicalis metamorphosis

Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during Xenopus tropicalis metamorphosis

Abstract Background Thyroid hormone (T3) plays an important role in vertebrate development. Compared to the postembryonic development of uterus-enclosed mammalian embryos, T3-dependent amphibian metamorphosis is advantageous for studying the function of T3 and T3 receptors (TRs) during vertebrate de...

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Bibliographic Details
Main Authors: Wonho Na, Liezhen Fu, Nga Luu, Yun-Bo Shi
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cell & Bioscience
Subjects:
Thyroid hormone receptor
Xenopus tropicalis
Anuran metamorphosis
Methyltransferase
tRNA
Stem cell
Online Access:http://link.springer.com/article/10.1186/s13578-020-00423-1

Internet

http://link.springer.com/article/10.1186/s13578-020-00423-1

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