Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation
<p>Abstract</p> <p>Background</p> <p>Ovarian cancer has the highest mortality rate of all gynecologic malignancy. The receptor tyrosine kinases (RTKs), including EGFR, ERBB2, PDGFR, VEGFR and MET, are activated in subsets of ovarian cancer, suggesting that these kinases...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-09-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://www.molecular-cancer.com/content/10/1/125 |