Targeting HSP90 in ovarian cancers with multiple receptor tyrosine kinase coactivation

<p>Abstract</p> <p>Background</p> <p>Ovarian cancer has the highest mortality rate of all gynecologic malignancy. The receptor tyrosine kinases (RTKs), including EGFR, ERBB2, PDGFR, VEGFR and MET, are activated in subsets of ovarian cancer, suggesting that these kinases...

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Bibliographic Details
Main Authors: Zhou Haimeng, Meng Fanguo, Ou Wenbin, Jiao Yisheng, Wang Aiyuan
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Molecular Cancer
Subjects:
Online Access:http://www.molecular-cancer.com/content/10/1/125