Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling

Pseudomonas aeruginosa adapts to octenidine via a combination of efflux and membrane remodelling

Bock et al. characterise the adaptation of Pseudomonas aeruginosa to the antiseptic octenidine, using whole genome sequencing, gene expression studies and metabolomics. They attribute this increased tolerance to synergistic changes in efflux and plasma membrane composition via mutations in SmvR, the...

Full description

Bibliographic Details
Main Authors: Lucy J. Bock, Philip M. Ferguson, Maria Clarke, Vichayanee Pumpitakkul, Matthew E. Wand, Paul-Enguerrand Fady, Leanne Allison, Roland A. Fleck, Matthew J. Shepherd, A. James Mason, J. Mark Sutton
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02566-4

Internet

https://doi.org/10.1038/s42003-021-02566-4

Similar Items