Impact of the rs1024611 Polymorphism of <i>CCL2</i> on the Pathophysiology and Outcome of Primary Myelofibrosis

Impact of the rs1024611 Polymorphism of <i>CCL2</i> on the Pathophysiology and Outcome of Primary Myelofibrosis

Single nucleotide polymorphisms (SNPs) can modify the individual pro-inflammatory background and may therefore have relevant implications in the MPN setting, typified by aberrant cytokine production. In a cohort of 773 primary myelofibrosis (PMF), we determined the contribution of the rs1024611 SNP...

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Bibliographic Details
Main Authors: Elena Masselli, Cecilia Carubbi, Giulia Pozzi, Antonio Percesepe, Rita Campanelli, Laura Villani, Giuliana Gobbi, Sabrina Bonomini, Giovanni Roti, Vittorio Rosti, Margherita Massa, Giovanni Barosi, Marco Vitale
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
primary myelofibrosis
myeloproliferative neoplasms
single nucleotide polymorphisms
CCL2
CCR2
Akt
Online Access:https://www.mdpi.com/2072-6694/13/11/2552

Internet

https://www.mdpi.com/2072-6694/13/11/2552

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