Using pre-existing microarray datasets to increase experimental power: application to insulin resistance.

Although they have become a widely used experimental technique for identifying differentially expressed (DE) genes, DNA microarrays are notorious for generating noisy data. A common strategy for mitigating the effects of noise is to perform many experimental replicates. This approach is often costly...

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Bibliographic Details
Main Authors: Bernie J Daigle, Alicia Deng, Tracey McLaughlin, Samuel W Cushman, Margaret C Cam, Gerald Reaven, Philip S Tsao, Russ B Altman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2845644?pdf=render