Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)

Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)

Liver mitochondrial metabolism plays an important role for glucose and lipid homeostasis and its alterations contribute to metabolic disorders, including fatty liver and diabetes. Here Perry et al. develop a method for the measurement of hepatic fluxes by using lactate and glucose tracers in combina...

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Bibliographic Details
Main Authors: Rachel J. Perry, Liang Peng, Gary W. Cline, Gina M. Butrico, Yongliang Wang, Xian-Man Zhang, Douglas L. Rothman, Kitt Falk Petersen, Gerald I. Shulman
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01143-w

Internet

https://doi.org/10.1038/s41467-017-01143-w

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