Molecular imaging of microglial activation in amyotrophic lateral sclerosis.

There is growing evidence of activated microglia and inflammatory processes in the cerebral cortex in amyotrophic lateral sclerosis (ALS). Activated microglia is characterized by increased expression of the 18 kDa translocator protein (TSPO) in the brain and may be a useful biomarker of inflammation...

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Main Authors: Philippe Corcia, Clovis Tauber, Johnnie Vercoullie, Nicolas Arlicot, Caroline Prunier, Julien Praline, Guillaume Nicolas, Yann Venel, Caroline Hommet, Jean-Louis Baulieu, Jean-Philippe Cottier, Catherine Roussel, Mickael Kassiou, Denis Guilloteau, Maria-Joao Ribeiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534121?pdf=render