Astrocyte glutathione maintains endothelial barrier stability

Astrocyte glutathione maintains endothelial barrier stability

Blood-brain barrier (BBB) impairment clearly accelerates brain disease progression. As ways to prevent injury-induced barrier dysfunction remain elusive, better understanding of how BBB cells interact and modulate barrier integrity is needed. Our metabolomic profiling study showed that cell-specific...

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Bibliographic Details
Main Authors: Sheng-Fu Huang, Alaa Othman, Alexey Koshkin, Sabrina Fischer, David Fischer, Nicola Zamboni, Katsuhiko Ono, Tomohiro Sawa, Omolara O. Ogunshola
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Neurovascular unit
Metabolic communication
Barrier stability
Tight junction
Blood-brain barrier
Redox balance
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172030361X

Internet

http://www.sciencedirect.com/science/article/pii/S221323172030361X

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