Mycobacterium tuberculosis-Specific T Cell Functional, Memory, and Activation Profiles in QuantiFERON-Reverters Are Consistent With Controlled Infection
Reversion of immune sensitization tests for Mycobacterium tuberculosis (M.tb) infection, such as interferon-gamma release assays or tuberculin skin test, has been reported in multiple studies. We hypothesized that QuantiFERON-TB Gold (QFT) reversion is associated with a decline of M.tb-specific func...
Main Authors: | Cheleka A. M. Mpande, Pia Steigler, Tessa Lloyd, Virginie Rozot, Boitumelo Mosito, Constance Schreuder, Timothy D. Reid, Nicole Bilek, Morten Ruhwald, Jason R. Andrews, Mark Hatherill, Francesca Little, Thomas J. Scriba, Elisa Nemes |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-08-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.712480/full |
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