An Adaptive Chlamydia trachomatis-Specific IFN-γ-Producing CD4+ T Cell Response Is Associated With Protection Against Chlamydia Reinfection in Women

An Adaptive Chlamydia trachomatis-Specific IFN-γ-Producing CD4+ T Cell Response Is Associated With Protection Against Chlamydia Reinfection in Women

Background: Adaptive immune responses that mediate protection against Chlamydia trachomatis (CT) remain poorly defined in humans. Animal chlamydia models have demonstrated that CD4+ Th1 cytokine responses mediate protective immunity against reinfection. To better understand protective immunity to CT...

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Bibliographic Details
Main Authors: Rakesh K. Bakshi, Kanupriya Gupta, Stephen J. Jordan, Xiaofei Chi, Shelly Y. Lensing, Christen G. Press, William M. Geisler
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
Chlamydia trachomatis
CD4+IFN-γ responses
reinfection
protection
T cell responses
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01981/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01981/full

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