Divalent cations can control a switch-like behavior in heterotypic and homotypic RNA coacervates

Abstract Liquid-liquid phase separation (LLPS) of RNA-protein complexes plays a major role in the cellular function of membraneless organelles (MLOs). MLOs are sensitive to changes in cellular conditions, such as fluctuations in cytoplasmic ion concentrations. To investigate the effect of these chan...

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Bibliographic Details
Main Authors: Paulo L. Onuchic, Anthony N. Milin, Ibraheem Alshareedah, Ashok A. Deniz, Priya R. Banerjee
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48457-x