3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II

3D quantification of changes in pancreatic islets in mouse models of diabetes type I and II

Diabetes is characterized by rising levels of blood glucose and is often associated with a progressive loss of insulin-producing beta cells. Recent studies have demonstrated that it is possible to regenerate new beta cells through proliferation of existing beta cells or trans-differentiation of othe...

Full description

Bibliographic Details
Main Authors: Urmas Roostalu, Jacob Lercke Skytte, Casper Gravesen Salinas, Thomas Klein, Niels Vrang, Jacob Jelsing, Jacob Hecksher-Sørensen
Format: Article
Language:English
Published: The Company of Biologists 2020-12-01
Series:Disease Models & Mechanisms
Subjects:
light-sheet fluorescence microscopy
tissue clearing
beta cells
insulin
inflammation
Online Access:http://dmm.biologists.org/content/13/12/dmm045351

Internet

http://dmm.biologists.org/content/13/12/dmm045351

Similar Items