Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic

Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic

Fluoroquinolone (FQ)-induced DNA damage in persisters could promote antibiotic resistance. Here, using time-lapse microscopy and genetic analyses, the authors show that after a single round of FQ treatment, SOS response in persisters accelerates the development of resistance to unrelated antibiotics...

Full description

Bibliographic Details
Main Authors: Theresa C. Barrett, Wendy W. K. Mok, Allison M. Murawski, Mark P. Brynildsen
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09058-4

Internet

https://doi.org/10.1038/s41467-019-09058-4

Similar Items