Mitochondrial Calcium Uptake Is Instrumental to Alternative Macrophage Polarization and Phagocytic Activity

Mitochondrial Calcium Uptake Is Instrumental to Alternative Macrophage Polarization and Phagocytic Activity

Macrophages are highly plastic and dynamic cells that exert much of their function through phagocytosis. Phagocytosis depends on a coordinated, finely tuned, and compartmentalized regulation of calcium concentrations. We examined the role of mitochondrial calcium uptake and mitochondrial calcium uni...

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Bibliographic Details
Main Authors: Serena Tedesco, Valentina Scattolini, Mattia Albiero, Mario Bortolozzi, Angelo Avogaro, Andrea Cignarella, Gian Paolo Fadini
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
macrophage
phagocytosis
innate immunity
second messenger
calcium
mitochondria
Online Access:https://www.mdpi.com/1422-0067/20/19/4966

Internet

https://www.mdpi.com/1422-0067/20/19/4966

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