Secreting-lux/pT-ClyA engineered bacteria suppresses tumor growth via interleukin-1β in two pathways

Secreting-lux/pT-ClyA engineered bacteria suppresses tumor growth via interleukin-1β in two pathways

Abstract Engineered Salmonella typhimurium (S.t-ΔpGlux/pT-ClyA) and attenuated Salmonella typhimurium (SL: Salmonella typhimurium with a defect in the synthesis of guanine 5′-diphosphate-3′-diphosphate) exhibit similar tumor targeting capabilities (Kim et al. in Theranostics 5:1328–1342, 2015; Jiang...

Full description

Bibliographic Details
Main Authors: Yuqin Wu, Zhicai Feng, Shengnan Jiang, Jing Chen, Yuefu Zhan, Jianqiang Chen
Format: Article
Language:English
Published: SpringerOpen 2019-11-01
Series:AMB Express
Subjects:
Engineered Salmonella typhimurium
IL-1β
TLR4
NLRP3
Colon cancer
Online Access:http://link.springer.com/article/10.1186/s13568-019-0910-6

Internet

http://link.springer.com/article/10.1186/s13568-019-0910-6

Similar Items