Is brain gliosis a characteristic of chronic methamphetamine use in the human?

Is brain gliosis a characteristic of chronic methamphetamine use in the human?

Animal data show that high doses of the stimulant drug methamphetamine can damage brain dopamine neurones; however, it is still uncertain whether methamphetamine, at any dose, is neurotoxic to human brain.Since gliosis is typically associated with brain damage and is observed in animal models of met...

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Bibliographic Details
Main Authors: Junchao Tong, Paul Fitzmaurice, Yoshiaki Furukawa, Gregory A. Schmunk, Dennis J. Wickham, Lee-Cyn Ang, Allan Sherwin, Tina McCluskey, Isabelle Boileau, Stephen J. Kish
Format: Article
Language:English
Published: Elsevier 2014-07-01
Series:Neurobiology of Disease
Subjects:
Methamphetamine
Gliosis
Glial fibrillary acidic protein
Vimentin
Heat shock protein-27
Glucose transporter-5
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611400076X

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http://www.sciencedirect.com/science/article/pii/S096999611400076X

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