Alteration of NO-producing system in the basal forebrain and hypothalamus of Ts65Dn mice: an immunohistochemical and histochemical study of a murine model for Down syndrome

Alteration of NO-producing system in the basal forebrain and hypothalamus of Ts65Dn mice: an immunohistochemical and histochemical study of a murine model for Down syndrome

Ts65Dn mice have been developed as a model for Down syndrome (DS). Because of its involvement in complex behaviors, including sexual and aggressive behaviors, we investigated the nitric oxide (NO) system in specific brain regions of these mutant mice (TS) after isolation-induced aggression. Male TS...

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Bibliographic Details
Main Authors: Stefano Gotti, Silvana Chiavegatto, Monica Sica, Carla Viglietti-Panzica, Randy J Nelson, GianCarlo Panzica
Format: Article
Language:English
Published: Elsevier 2004-08-01
Series:Neurobiology of Disease
Subjects:
Down syndrome
Ts65Dn mouse
Aggression
Nitric oxide
Paraventricular nucleus
Diagonal band
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104001007

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http://www.sciencedirect.com/science/article/pii/S0969996104001007

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