Novel rank-based statistical methods reveal microRNAs with differential expression in multiple cancer types.

BACKGROUND:MicroRNAs (miRNAs) regulate target genes at the post-transcriptional level and play important roles in cancer pathogenesis and development. Variation amongst individuals is a significant confounding factor in miRNA (or other) expression studies. The true character of biologically or clini...

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Bibliographic Details
Main Authors: Roy Navon, Hui Wang, Israel Steinfeld, Anya Tsalenko, Amir Ben-Dor, Zohar Yakhini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2777376?pdf=render