Aneuploidy Mechanisms in Human Colorectal Preneoplastic Lesions and Barrett’s Esophagus. Is There a Role for K-Ras and p53 Mutations?

The link of aneuploidy and heteroploidy in human solid tumours with early genetic events is poorly understood. The study of human preneoplastic precursor lesions, i.e., colorectal adenomas, chronic ulcerative colitis lesions, and Barrett’s esophagus, as considered in this review, appears particularl...

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Bibliographic Details
Main Author: Walter Giaretti
Format: Article
Language:English
Published: Hindawi Limited 1997-01-01
Series:Analytical Cellular Pathology
Online Access:http://dx.doi.org/10.1155/1997/264135