BRAF and MAP2K1 mutations in hairy cell leukemia and splenic marginal zone B-cell lymphoma

DNA samples from patients with hairy cell leukemia (HCL) and splenic marginal zone B-cell lymphoma (MZBCL) for BRAF and MAP2K1 activating mutations were analyzed. V600E mutation of BRAF was detected in 39 (98 %) of 40 patients with hairy cell leukemia, and no patient with MZBCL. In none of the patie...

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Bibliographic Details
Main Authors: I. A. Yakutik, L. S. Al’-Radi, H. L. Julhakyan, B. V. Biderman, A. B. Sudarikov
Format: Article
Language:Russian
Published: ABV-press 2016-03-01
Series:Onkogematologiâ
Subjects:
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/179