The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization

The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization

Summary: Despite recent progress in engineering native trimeric HIV-1 envelope glycoprotein (Env) mimics as vaccine candidates, Env trimers often induce vaccine-matched neutralizing antibody (NAb) responses. Understanding the specificities of autologous NAb responses and the underlying molecular mec...

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Bibliographic Details
Main Authors: Lin Lei, Yuhe R. Yang, Karen Tran, Yimeng Wang, Chi-I Chiang, Gabriel Ozorowski, Yongli Xiao, Andrew B. Ward, Richard T. Wyatt, Yuxing Li
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719303559

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http://www.sciencedirect.com/science/article/pii/S2211124719303559

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