Pharmacometabolomics of Bronchodilator Response in Asthma and the Role of Age-Metabolite Interactions

Pharmacometabolomics of Bronchodilator Response in Asthma and the Role of Age-Metabolite Interactions

The role of metabolism in modifying age-related differential responses to asthma medications is insufficiently understood. The objective of this study was to determine the role of the metabolome in modifying the effect of age on bronchodilator response (BDR) in individuals with asthma. We used longi...

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Bibliographic Details
Main Authors: Rachel S. Kelly, Joanne E. Sordillo, Sharon M. Lutz, Lydiana Avila, Manuel Soto-Quiros, Juan C. Celedón, Michael J. McGeachie, Amber Dahlin, Kelan Tantisira, Mengna Huang, Clary B. Clish, Scott T. Weiss, Jessica Lasky-Su, Ann Chen Wu
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Metabolites
Subjects:
bronchodilator response
age by metabolite interaction
asthma
metabolomics
pharmacometabolomics
GABA
cholesterol esters
childhood asthma management program
genetic epidemiology of asthma in Costa Rica
Online Access:https://www.mdpi.com/2218-1989/9/9/179

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https://www.mdpi.com/2218-1989/9/9/179

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